【摘 要】
:
Objective:Lymph node status is critical when selecting treatment methods for patients with early gastric cancer(EGC).The aim of this study was to assess the diagnostic value of computed tomography(CT)for detection of lymph node metastasis(LNM)in patients
【机 构】
:
Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Gastroint
论文部分内容阅读
Objective:Lymph node status is critical when selecting treatment methods for patients with early gastric cancer(EGC).The aim of this study was to assess the diagnostic value of computed tomography(CT)for detection of lymph node metastasis(LNM)in patients with EGC.Methods:We retrospectively analyzed patients who had pathologically confirmed EGC between November 2010 and January 2019.After 1:1 propensity score matching,65 patients with LNM and 65 patients without LNM were retained for comparison.The long diameter(LD)and short diameter(SD)of all visualized lymph nodes in all stations were recorded.The diagnostic value of LNM was assessed with receiver operating characteristic analysis.Results:Among 130 patients,we found a total of 558 lymph nodes on the CT images.Among the diagnostic indicators,the number,sum of LD and sum of SD of lymph nodes greater than 3 mm had better discrimination.The areas under the curve were all greater than 0.75.As for different regions,the optimal cutoff values of number,the sum of LD and sum of SD were determined as follows:overall,≥4,19.9 mm and 13.5 mm;left gastric artery basin,≥3,15.7 mm and 8.6 mm;right gastroepiploic artery basin,≥2,8.6 mm and 7.0 mm.Conclusions:CT is valuable for diagnosing LNM in EGC patients.The number,sum of LD and sum of SD of lymph nodes greater than 3 mm are preferable indicators.Different regional lymph nodes have different optimal criteria for predicting LNM in ECG patients.
其他文献
目的 建立闹羊花中闹羊花毒素Ⅱ、Ⅲ、Ⅴ的定量分析方法,并测定不同产地、花期闹羊花毒素含量,用于闹羊花药材的质量评价及产地、采收期的选择.方法 采用Waters C18色谱柱(250 mm×4.6 mm,5 μm)色谱柱,甲醇(A)-水(B)流动相,建立高效液相色谱联合电雾式检测器(HPLC-CAD)方法,并进行方法学验证,对17批不同产地、5批不同花期药材中3种闹羊花毒素进行含量测定,并聚类分析.结果 所建立的分析方法简便,准确度和精密度良好,能作为闹羊花药材常规定量评价方法;不同产地闹羊花药材可聚为3类
心血管疾病是心脏和血管方面相关的疾病,包括高血压、高脂血症、血栓栓塞、冠心病和心力衰竭等.心血管疾病严重危害人类健康,是全球范围内造成死亡的最主要原因.维护心血管系统健康的关键因素是对疾病的预防.植物精油及其部分成分能舒张血管、降血压、抗心肌缺血、预防和改善动脉粥样硬化、抗血小板聚集以及抗心律失常,从而对心血管系统具有保护作用.植物精油有益于人体的心血管系统,但需要更多的临床研究和安全性研究的证据.
Objective:This study aimed to develop and validate a risk scoring system to identify high-risk individuals carrying malignant lesions in stomach for tailored gastric cancer screening.Methods:A gastric cancer risk scoring system(GC-RSS)was developed based
Objective:Computer-aided diagnosis using deep learning algorithms has been initially applied in the field of mammography,but there is no large-scale clinical application.Methods:This study proposed to develop and verify an artificial intelligence model ba
Objective:Limited evidence is available regarding the associations of centralization with gastric cancer patients\'quality of care in high surgical volume settings.The current study aimed to explore the effects of hospital volume and the Herfindahl-Hirs
The profiling of plasma cell-free DNA(cfDNA)is becoming a valuable tool rapidly for tumor diagnosis,monitoring and prognosis.Diverse plasma cfDNA technologies have been in routine or emerging use,including analyses of mutations,copy number alterations,gen
动物作为一种自然资源具有诸多用途.新中国成立以来,为保护动物资源、规范动物繁育养殖、防范动物疫病给公共卫生安全带来风险,我国颁布了系列法律法规.尤其是新型冠状病毒肺炎疫情以来,我国确立了有史以来最严格的野生动物利用制度,启动了多部法律法规的制修订工作,也使得动物类中药材(以下简称“动物药”)的利用将面临更为严格的审查.探讨了我国现有动物相关法律法规对动物药利用的影响,并对动物药的发展提出几点建议.
Objective:Local recurrence of hepatocellular carcinoma(HCC)after radiofrequency ablation(RFA)treatment remains a serious problem.Tumor-initiating cells(TICs)are thought to be responsible for tumor relapse.Here,we investigated the effect of the TIC differe
This decade has seen remarkable advances in the field of high-throughput single cell techniques.Single-cell RNA sequencing(scRNA-seq)has proven to be a powerful strategy to study the heterogeneity in clinical samples,providing an unbiasedapproach to uncov
背景与目的:长链非编码RNA(long non-coding RNA,lncRNA)ARAP1-AS1在多种肿瘤中异常表达,但其在肾透明细胞癌(clear cell renal cell carcinoma,ccRCC)中的作用尚不清楚.探讨ARAP1-AS1在ccRCC中的生物学作用.方法:通过GEPIA数据库分析ARAP1-AS1在ccRCC组织中的表达及其与临床病理学特征及患者生存率的关系.采用实时荧光定量聚合酶链反应(real-time fluorescence quantitative poly