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目的 探讨百忧解 (fluoxetinehydrochloride;prozac)治疗脑卒中后抑郁患者抑郁情绪、认知功能及神经功能缺损程度的疗效。方法 选择 82例急性脑卒中患者 ,经DSM Ⅳ诊断脑卒中后抑郁 ,评定百忧解治疗前后汉密尔顿抑郁量表得分、认知功能及神经功能缺损程度的变化。结果 脑卒中后抑郁患者存在认知功能下降及神经功能缺损程度加重 ;百忧解可改善脑卒中后抑郁患者的抑郁情绪、认知功能及神经功能缺损程度。结论 百忧解适用于治疗脑卒中后抑郁患者
Objective To investigate the curative effect of fluoxetine hydrochloride (prozac) on depression, cognitive function and neurological deficit in patients with post-stroke depression. Methods 82 patients with acute stroke were selected and DSM Ⅳ was used to diagnose depression after stroke. The changes of Hamilton Depression Inventory score, cognitive function and neurological impairment were evaluated before and after treatment with Prozac. Results The patients with post-stroke depression had decreased cognitive function and neurological deficits. Prozac could improve depression, cognitive function and neurological deficits in patients with post-stroke depression. Conclusions Prozac is suitable for the treatment of post-stroke depression