牙齿在正常状态下存在脱矿和再矿化的动态平衡过程,抑制牙齿脱矿并促进其再矿化是治疗龋病的一个重要途径。牙齿的再矿化是典型的生物矿化过程,有机基质可以作为模板诱导无机矿物在有机-无机界面上定向组装,改变晶体生长的过程及其最终形貌,因此是矿化成核过程中关键的调控因素。研究有机基质诱导矿化的机理和开发能促进牙齿再矿化的有机高分子材料对于龋病的治疗意义重大。20世纪 In normal condition, there is dynamic equilibrium process of demineralization and remineralization. Suppression of dental demineralization and its remineralization are an important way to treat dental caries. Remineralization of teeth is a typical biomineralization process. Organic matrices can be used as a template to induce the directional assembly of inorganic minerals on the organic-inorganic interface to change the crystal growth process and the final morphology. Therefore, it is a key mineralization process Regulatory factors. It is of great significance to study the mechanism of organic matrix inducing mineralization and to develop organic macromolecule materials that can promote the remineralization of dental caries. 20th Century