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1960年Miller和Good分别报告胸腺对免疫的重要意义。1965年Goldstein和White自小牛胸腺提取胸腺素(Thymosi)并对其生物学和药理学特点进行了鉴定,胸腺素是胸腺分泌的一种多肽蛋白质激素,它参与机体细胞免疫反应,有促使淋巴干细胞及较成熟的淋巴细胞分化为成熟的,有细胞免疫活性的T淋巴细胞,因此胸腺素是一种细胞免疫的增强剂,以调整机体的免疫功能。近几年来胸腺素已被应用于临床,治疗免疫缺陷病、变态反应病、自身免疫病、肿瘤以及细菌、病毒、霉菌感染性疾病。我们在山东省科委及省卫生、商业、教育厅和医药局的领导下,于1977年开始临床试用并进行实验研究。近4年来先后用山东莱阳生物化
In 1960, Miller and Good reported the importance of the thymus on immunity. In 1965, Goldstein and White extracted thymosin from calf thymus and identified its biological and pharmacological characteristics. Thymosin is a polypeptide hormone secreted by the thymus, which is involved in the cellular immune response of the body, Stem cells and more mature lymphocytes differentiate into mature, cellular immune activity of T lymphocytes, thymosin is a cellular immunity enhancer to adjust the body’s immune function. In recent years, thymosin has been used clinically to treat immunodeficiency diseases, allergic diseases, autoimmune diseases, tumors, as well as bacterial, viral and fungal infectious diseases. Under the leadership of the Shandong Provincial Science and Technology Commission and the Provincial Department of Health, Commerce, Education and Pharmacy, we started clinical trials in 1977 and conducted experimental studies. Nearly 4 years has Laiyang biochemical