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目的:回顾性分析3.0 T MRI膀胱癌不同b值的弥散加权成像(DWI)表现和表观弥散系数(ADC),探讨高场强MRI最佳b值的选取。方法:对30例经病理证实为膀胱癌的患者进行MRI常规成像及DWI检查。梯度扩散因子b值分别取700 s/mm2、1 000 s/mm2和1 500 s/mm2。观察膀胱癌不同b值的DWI表现,测量肿瘤信噪比(SNRC)、肿瘤对正常膀胱壁和尿液的对比信噪比(CNRCB、CNRCU)及测量不同b值时肿瘤的ADC值,并进行统计分析。结果:DWI可显示所有肿瘤病灶,呈偏高信号肿块影;随着b值增加,肿瘤SNRC下降,而CNRCB、CNRCU升高,差异有统计学意义(P<0.05);随着b值增加,肿瘤平均ADC值虽有减小趋势,但差异尚无统计学意义(F=3.04,P>0.05)。结论:当b值取1 500 s/mm2时,在不影响病灶显示的情况下可获得较高的对比信噪比和相对准确的ADC值,有助于膀胱癌的早期发现和准确分期。
OBJECTIVE: To retrospectively analyze the diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC) of different b values in 3.0 T MRI bladder cancer and to explore the best b value selection in high field MRI. Methods: Thirty patients with pathologically confirmed bladder cancer underwent conventional MRI and DWI. Gradient diffusion factor b values were taken 700 s / mm2, 1000 s / mm2 and 1500 s / mm2. We observed the different b values of bladder cancer DWI performance, measurement of tumor signal to noise ratio (SNRC), tumor normal bladder wall and urine contrast signal-to-noise ratio (CNRCU) and ADC values ?? measured at different b values of the tumor, Statistical Analysis. Results: DWI showed all tumor lesions with hyperintense signal mass. With the increase of b value, the tumor SNRC decreased and CNRCB, CNRCU increased, the difference was statistically significant (P <0.05). With the increase of b value, Although the average ADC value of the tumor decreased, the difference was not statistically significant (F = 3.04, P> 0.05). CONCLUSION: When the b value is 1500 s / mm2, a higher contrast signal-to-noise ratio and a relatively accurate ADC value can be obtained without affecting the lesion display, which is helpful for the early detection and accurate staging of bladder cancer.