目的:研究高血压病患者血胰岛素、血糖和血脂水平的变化以及相关的影响因素。方法:对86例原发性高血压患者进行口服葡萄糖耐量试验(OGTT)和胰岛素释放试验(IRT),同时测定血中胰岛素、血糖和血胆固醇、甘油三酯的水平。结果:高血压患者血胰岛素、血糖、血胆固醇及甘油三酯水平升高。结论:高血压患者存在胰岛素抵抗(ISR),而且与血压、年龄和体重指数密切相关。 Objective: To study the changes of blood insulin, blood glucose and blood lipid levels and related factors in hypertensive patients. Methods: Oral glucose tolerance test (OGTT) and insulin release test (IRT) were performed in 86 patients with essential hypertension. The blood levels of insulin, blood glucose, blood cholesterol and triglyceride were measured simultaneously. Results: Hypertensive patients with elevated blood insulin, blood glucose, blood cholesterol and triglyceride levels. Conclusion: Hypertensive patients have insulin resistance (ISR), and are closely related to blood pressure, age and body mass index.