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目的 :提出阴道微生态亚失调状态的概念及其特征与机制。方法 :选取门诊及妇女健康普查患者 2 0 9例。健康妇女 10 2例为对照组 ;以临床主治外阴不适或偶有瘙痒 ,阴道分泌物增多 ,分泌物检查排除特异性微生物感染及细菌性阴道炎、严重宫颈炎的患者 10 7例为观察组 ;取阴道分泌物经倍比稀释接种于各培养基上进行需氧及厌氧培养 ,鉴定并检测微生物种类 ,活菌计数 ,检测菌种为乳酸杆菌、白色念珠菌、类杆菌、大肠埃希菌、链球菌 ,并同时测定阴道 p H值及清洁度。结果 :p H值无显著变化 (P>0 .0 5 ) ,清洁度观察组变化明显 ( °～ °) ;各菌种活菌计数观察组与对照组相比变化显著 (P>0 .0 5 )。结论 :阴道微生境在内外因素作用下存在一种过渡状态 ,该状态呈可逆性 ,在机体抵抗力增加或 /和去掉诱因后可自然恢复 ,如进一步发展可导致特异性或非特异性阴道炎、宫颈炎。作者由此提出“阴道微生态亚失调状态”概念。
Objective: To put forward the concept of vaginal microecological sub-imbalance and its characteristics and mechanisms. Methods: 209 outpatients and women’s health census patients were selected. 102 cases of healthy women as the control group; clinical indications of vulvar discomfort or occasional pruritus, increased vaginal discharge, secretions examination to exclude specific microbial infections and bacterial vaginitis, severe cervicitis in patients with 107 cases of observation group; Vaginal secretions were inoculated on each culture medium for aerobic and anaerobic culture. The microorganisms were identified and tested for viable count. The tested strains were Lactobacillus, Candida albicans, Bacteroides, Escherichia coli , Streptococcus, and vaginal p H value and cleanliness at the same time. Results: There was no significant change in the value of p H (P> 0.05), and the degree of cleanliness in observation group changed significantly (° ~ °). The viable count in each strain showed significant changes compared with the control group (P 0. 0 5). CONCLUSIONS: Vaginal micro-organism has a transitional state under the action of internal and external factors. The state is reversible. It can recover spontaneously after the body’s resistance is increased or / and its causes are removed. If further development can lead to specific or non-specific vaginitis, Cervicitis. The author put forward the concept of “vaginal micro-ecological sub-disorders state”.