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以往虽有多人报告自身免疫性甲状腺炎与系统性红斑狼疮相并发的病例。Becker曾报告506例患自身免疫性甲状腺炎者,约有0.2%并发系统性红斑狼疮。其他尚有多人报告类似情况,但无报告与皮肤型红斑狼疮相并发的病例。作者报告一例19岁女孩,患有盘状红斑狼疮,曾持续服用氯喹治疗4年,皮损无好转。皮损分布于面部及前臂。正常皮肤的组织检查,在血管壁周围及基底膜部有IgG、IgM、及补体沉积,提示可能为移行性皮肤LE或SLE,但无其他SLE证据,抗核抗体,LE细胞试验等均阴性。T_3RIA,T_4-I,TSH等化验室检查,证实患者甲状腺机能减退,实验上证实有自
Although in the past many people report autoimmune thyroiditis and systemic lupus erythematosus concurrent cases. Becker has reported 506 cases of autoimmune thyroiditis, about 0.2% of patients with systemic lupus erythematosus. Others There are many people report a similar situation, but no cases of concurrent with cutaneous type lupus erythematosus. The authors report a 19-year-old girl with discoid lupus erythematosus who had been on chloroquine for 4 years and had no improvement in her skin lesions. Lesions spread over the face and forearm. Normal skin tissue examination, in the vascular wall and basement membrane with IgG, IgM, and complement deposition, suggesting that may be transitional skin LE or SLE, but no other SLE evidence, antinuclear antibodies, LE cell test were negative. T_3RIA, T_4-I, TSH and other laboratory tests confirmed that patients with hypothyroidism, experimentally confirmed to have