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【目的】探讨垂体后叶素两点注射法在腹腔镜下输卵管妊娠切开术中的应用价值。【方法】将2006年6月-2007年12月我院妇科未破裂输卵管妊娠患者200例,均行腹腔镜下输卵管切开术,分成3组,其中术中两点注射垂体后叶素组(观察1组)72例、单点注射垂体后叶素组(观察2组)62例和未使用垂体后叶素组(对照组)66例。比较3组的手术时间、术中出血量、术后最高体温、手术并发症等。【结果】观察1组和观察2组的手术时间、术中出血量均明显少于对照组(P<0.05),观察1组少于观察2组(P<0.05)。观察1组的持续性宫外孕发生率低于对照组(P<0.01),观察2组的持续性宫外孕发生率与观察1组和对照组比较无显著性差异(P>0.05)。3组术后最高体温无明显差异(P>0.05)。使用垂体后叶素的患者无1例不良反应发生。【结论】在腹腔镜下输卵管切开术中应用垂体后叶素注射,能减少术中出血,缩短手术时间并减少持续性宫外孕等并发症的发生,在患侧宫角及输卵管系膜两点注射法优于输卵管系膜单点注射法,两种方法都安全可靠。
【Objective】 To investigate the value of pituitrin two-point injection in laparoscopic tubal pregnancy incision. 【Methods】 200 cases of unruptured tubal pregnancy in our hospital from June 2006 to December 2007 were performed laparoscopic tubal incision and divided into 3 groups. 72 cases in observation group 1), 62 cases in single injection of pituitrin group (observation group 2) and 66 cases in pituitrin group (control group). The operation time, intraoperative blood loss, postoperative maximum body temperature, surgical complications and so on were compared. 【Results】 The operation time and intraoperative blood loss of observation group 1 and observation group 2 were significantly less than those of the control group (P <0.05). The observation group 1 was less than the observation group 2 (P <0.05). The incidence of persistent ectopic pregnancy in observation group 1 was lower than that in control group (P <0.01). The incidence of persistent ectopic pregnancy in observation group 1 was not significantly different from that in observation group 1 and control group (P> 0.05). There was no significant difference between the three groups in postoperative maximum body temperature (P> 0.05). No adverse reactions occurred in patients using pituitrin. 【Conclusion】 The application of pituitrin injection in laparoscopic tubal incision can reduce the intraoperative bleeding, shorten the operation time and reduce the occurrence of persistent ectopic pregnancy complications. In the ipsilateral hysteroid and tubal mesangial two points Injection is superior to tubal single point injection, both methods are safe and reliable.