论文部分内容阅读
9例恶性间皮瘤(MM)免疫组化CEA染色均呈阴性,对照组36例肺腺癌30例阳性。Vimentin染色9例MM中8例阳性,对照组中5例肺腺癌均为阴性。组织化学胶质铁(CI)染色9例MM中8例阳性,再行透明质酸酶(HCI)胶质铁染色则均呈阴性,对照组5例肺腺癌CI染色4例阳性,再行HCI染色仍为阳性。电镜下MM瘤细胞表面可见密集成刷状或蓬发样微绒毛,且细而长,浆内见丰富张力微丝,肺腺癌则无。AgNOR染色MM瘤细胞核内AgNOR颗粒总平均值大,直径≥2.5μm以上细胞数多,与反应性增生间皮细胞有显著性差别(P<0.01)。文中我们对上述MM鉴别诊断方法的价值进行了讨论。
9 cases of malignant mesothelioma (MM) immunohistochemical CEA staining were negative, and the control group of 36 cases of lung adenocarcinoma were positive in 30 cases. Vimentin staining was positive in 8 of 9 cases of MM, and 5 cases of lung adenocarcinoma were negative in control group. Histochemical staining with colloidal iron (CI) was positive in 8 cases in 9 cases of MM, and hyaluronic acid (HCI) glial staining was negative in all cases. In the control group, 4 cases of lung adenocarcinoma were positive for CI staining. HCI staining remained positive. Under the electron microscope, the surface of the MM tumor cells was densely integrated with brush-like or puff-like microvilli, and they were thin and long, and the microfilaments were abundant in the pulp. Lung adenocarcinoma was absent. The average AgNOR granules in the nucleus of AgNOR-stained MM tumors were large, and the number of cells with diameters ≥2.5 μm was more than that of the reactive hyperplastic mesothelial cells (P<0.01). In this paper we discuss the value of the above MM differential diagnosis method.