激素治疗晚期乳腺癌的疗效已被公认,而孕激素治疗晚期乳腺癌的报道却很少。自1951年Escher 首先报道孕激素治疗晚期乳腺癌有效以来,随着基础和临床研究的进展,临床应用孕激素治疗晚期乳腺癌已取得初步疗效,但未广泛采用。本文就近年内孕激素治疗乳腺癌的概况作一综述。 The efficacy of hormone therapy for advanced breast cancer has been recognized, and progesterone treatment of advanced breast cancer is rarely reported. Since Escher first reported in 1951 that progesterone was effective in treating advanced breast cancer, with the development of basic and clinical research, clinical progestogen treatment of advanced breast cancer has achieved preliminary results, but it has not been widely adopted. This article reviews the progesterone treatment of breast cancer in recent years.