长久以来认为甲亢症状和体征的产生可能与交感神经系统有关,通过β肾上腺素能阻滞剂如心得安的治疗,数天后很多甲亢患者的外周表现和临床症状得到减轻,有力地支持上述看法,并且还指明α及β肾上腺素能的显效药有刺激甲状腺的性质。显然在人类甲状腺滤泡内有交感神经末梢的形态学基础,药物可直接影响到甲状腺滤泡细胞的交感神经系统。 It has long been thought that the generation of symptoms and signs of hyperthyroidism may be related to the sympathetic nervous system. Through the treatment of β-adrenergic blockers such as propranolol, the peripheral manifestations and clinical symptoms of many patients with hyperthyroidism are alleviated in a few days, strongly supporting the above- It has also been shown that α and β adrenergic agonists can stimulate the thyroid gland. Obviously in human thyroid follicles within the morphological basis of sympathetic nerve endings, the drug can directly affect thyroid follicular cells of the sympathetic nervous system.