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目的观察2型糖尿病患者消化间期胃肠运动的特征。方法选取我院2011年10月-2013年1月收治的57例2型糖尿病患者设为实验组,选取同期25名健康志愿者设为对照组。用胃十二指肠测压技术对两组人员进行消化间期胃肠移行性复合运动(MMC)检测,测定时间240-360min。结果实验组患者MMC正常者明显低于对照组(P<0.01),实验组MMCⅢ期缺失者高于对照组(P<0.01),MMCⅡ期持续时间长于对照组(P<0.05),MMCⅢ期胃窦部收缩频率和波幅低于对照组(P<0.05)。结论糖尿病患者消化间期胃肠运动障碍可主要表现为MMCⅢ期缺失、Ⅱ期持续时间延长以及胃窦部收缩力减弱,胃十二指肠测压可作为糖尿病患者胃肠运动功能障碍诊断及治疗的有效措施。
Objective To observe the characteristics of gastrointestinal motility during digestive tract in type 2 diabetic patients. Methods Fifty-seven patients with type 2 diabetes treated in our hospital from October 2011 to January 2013 were selected as the experimental group and 25 healthy volunteers were selected as the control group. The gastroduodenal pressure-measuring technique was used to detect the intestine-gastrointestinal metaplasia (MMC) between the two groups. The determination time was 240-360min. Results The MMC in the experimental group was significantly lower than that in the control group (P <0.01). The MMCⅢphase deletion in the experimental group was higher than that in the control group (P <0.01), and the duration of MMCⅡphase was longer than that in the control group (P <0.05) Sinus contracting frequency and amplitude were lower than the control group (P <0.05). Conclusions The gastrointestinal motility disorder in patients with diabetes mellitus can be mainly manifested as the lack of MMC Ⅲ phase, the prolonged duration of Ⅱ and gastric antrum contractility weakened, gastroduodenal manometry can be used as a diagnosis and treatment of gastrointestinal motility disorders in patients with diabetes Effective measures.