一、Sweet 综合征的回顾远在1949年,Sweet 就开始收集一组少见的病例,到1964年他首先报告了8个病例,指出该病具有发热、疼痛性隆起性红斑、血中嗜中性白细胞增多、组织病理表现为真皮浅层有显著的嗜中性白细胞浸润等四项主要特征,命名为急性发热性嗜中性白细胞增多性皮病。1968年 Sweet 本人又补充报告了4例具有相同症状的患者,并且进一步提出在 First, the review of Sweet Syndrome As far back as 1949, Sweet began to collect a rare group of cases, and in 1964 he first reported eight cases, indicating that the disease has fever, painful erythema macularis, blood neutrophilic Leukocytosis, histopathological manifestations of the dermis shallow significant neutrophil infiltration and other four major features, named acute febrile neutrophilic leukemia. In 1968 Sweet himself added that four patients with the same symptoms were reported, and further suggested