论文部分内容阅读
目的 :探讨89Sr(锶 )治疗骨质疏松性骨折及其引起顽固性疼痛的疗效。方法 :对12例骨质疏松性骨折患者静脉注射89Sr,比较治疗前后患者疼痛程度及骨质量 (BMD)的改变 ,并与对照组比较。结果 :静脉注射 89Sr5～10天后 ,11例疼痛完全缓解(Ⅰ级) ,1例明显好转、仅轻度疼痛(Ⅱ级) ,总有效率100 %。治疗前后腰椎BMD百分率变化:显效4例 ,有效5例 ,无效3例 ,总有效率75 %。与对照组比较效果明显(P<0.05)。结论 :静脉注射 89Sr能有效治疗骨质疏松性骨折及其引起的顽固性疼痛。
Objective: To investigate the effect of 89Sr (strontium) in the treatment of osteoporotic fracture and its refractory pain. Methods: Twelve patients with osteoporotic fracture were treated with intravenous injection of 89Sr. The changes of pain and bone mass before and after treatment were compared with those of the control group. Results: After 5 to 10 days of intravenous injection of 89Sr, 11 cases of pain were completely relieved (grade Ⅰ), 1 case improved significantly, only slight pain (grade Ⅱ), the total effective rate was 100%. Before and after treatment, the percentage of lumbar BMD changes: 4 cases markedly effective in 5 cases, 3 cases, the total effective rate of 75%. Compared with the control group, the effect was obvious (P <0.05). Conclusion: 89Sr can effectively treat osteoporotic fracture and refractory pain caused by it.