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目的分析血清中癌胚抗原(CEA)、糖类抗原125(CA125)水平在妇科肿瘤中临床应用价值。方法选取我院2010年2月—2012年9月治疗的妇科肿瘤患者60例,分为良性妇科肿瘤组30例,恶性妇科肿瘤组30例,另选取我院门诊妇科体检非妇科肿瘤患者30例为对照组,用化学发光测定仪检测所有患者血清中CEA、CA125水平。结果对照组、良性妇科肿瘤组及恶性妇科肿瘤组血清CEA、CA125水平比较,差异有统计学意义(P<0.05),恶性妇科肿瘤组血清CEA、CA125水平高于对照组和良性妇科肿瘤组(P<0.01),良性妇科肿瘤组血清CEA、CA125水平高于对照组(P<0.05)。结论血清CEA、CA125水平对妇科恶性肿瘤的确诊有较好的专属性和有效性,对妇科恶性肿瘤的早期确诊有较好参考意义。
Objective To analyze the clinical value of serum carcinoembryonic antigen (CEA) and carbohydrate antigen 125 (CA125) in gynecological tumors. Methods 60 patients with gynecologic cancer treated in our hospital from February 2010 to September 2012 were selected and divided into 30 cases of benign gynecologic tumor and 30 cases of malignant gynecologic tumor and 30 cases of gynecological cancer of gynecological examination in our hospital As control group, all patients with chemiluminescence detector CEA, CA125 levels. Results The serum levels of CEA and CA125 in the control group, benign gynecologic tumor group and malignant gynecologic tumor group were significantly different (P <0.05). The levels of serum CEA and CA125 in the malignant gynecologic tumor group were higher than those in the control group and the benign gynecologic tumor group P <0.01). The serum levels of CEA and CA125 in benign gynecologic tumor group were higher than those in control group (P <0.05). Conclusions Serum CEA and CA125 levels have a good specificity and validity for the diagnosis of gynecologic malignancies, and have good reference value for the early diagnosis of gynecologic malignancies.