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近年来,成人感染肺炎支原体呈增多趋势,阿奇霉素由于疗效确切,可作为首选药物。随着其临床应用范围的逐渐扩大,药品不良反应也屡见报道。该文报道1例28岁男性,因患肺炎支原体肺炎而予以阿奇霉素静脉滴注,第一次由于滴速较快,出现频发室性期前收缩,第二次减慢滴速后,仍发生室性期前收缩,改为口服阿奇霉素后,无异常反应发生,直至患者疾病治愈,均未发生不适情况。分析原因可能为静脉使用该药时吸收较快有关。本例提示为了减少阿奇霉素不良反应的发生,要尽量使用口服制剂,若必须使用静脉制剂时,则应严格控制其输液速度和浓度,以减少不良反应的发生。
In recent years, adult infected with Mycoplasma pneumoniae showed an increasing trend, azithromycin as the exact effect, can be used as the drug of choice. With the gradual expansion of its clinical application, adverse drug reactions are also frequently reported. This article reports a case of 28-year-old male suffering from mycoplasma pneumonia due to azithromycin intravenous infusion, the first time due to rapid drip rate, frequent ventricular contractions occur frequently, the second slow drip rate still occurs Ventricular premature contractions, changed to oral azithromycin, no abnormal reaction occurs, until the patient is cured, no discomfort. Analysis of the reasons may be intravenous use of the drug faster absorption related. This example prompts in order to reduce the incidence of azithromycin adverse reactions, we should try to use oral preparations, if intravenous preparations must be used, it should be strictly controlled infusion rate and concentration to reduce the incidence of adverse reactions.