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大家公认黄体期功能主要依赖于排卵前及排卵期前后滤泡情况。虽然有些报告论及对月经周期正常的(包括怀疑黄体期不足者)不孕妇女用(三苯氧胺)tamoxifen 治疗,在滤泡期有抗雌素作用。此药对滤泡生成的作用机理尚有争论。曾报导 ta-moxifen 使用于黄体期不足病人,可延长黄体期,并使黄体期孕酮总和显著增高。本研究目的是明确对有正常月经周期的不孕妇女使用 Tamoxifen 改善滤泡生成中的作用机理。
It is generally acknowledged that luteal phase function mainly depends on the condition of follicle before ovulation and before ovulation. Although some reports dealt with tamoxifen (tamoxifen) for infertile women with normal menstrual cycles (including those with suspected loss of luteal phase), there are antiestrogenic effects during the follicular phase. This medicine on the formation of follicular mechanism of action is still controversial. It has been reported that ta-moxifen is used in patients with insufficient luteal phase to prolong the luteal phase and significantly increase the sum of progesterone in the luteal phase. The aim of this study was to determine the mechanism by which Tamoxifen improves follicle formation in infertile women with normal menstrual cycles.