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目的观察妊娠期糖尿病对孕妇和胎儿结局的影响。方法选取医院收治的妊娠期糖尿病孕妇80例作为观察组,同期妊娠非糖尿病孕妇80例作为对照组,观察2组妊娠结局、高危因素对孕妇和胎儿结局的影响。结果观察组空腹血糖、三酰甘油等指标均显著高于对照组(P<0.01)。观察组早产率、子痫前期、巨大胎儿的妊娠结局与对照组比较,差异有统计学意义(P<0.05)。经回归分析,妊娠期糖尿病高危因素对孕妇和胎儿结局有一定的影响,主要影响因素有空腹血糖(FPG)、三酰甘油(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、游离脂肪酸(FFA)。结论妊娠期糖尿病对孕妇和胎儿结局有较大影响,加强对妊娠期糖尿病的控制,降低其对妊娠结局产生的影响。
Objective To observe the effect of gestational diabetes on the outcome of pregnant women and fetuses. Methods Eighty pregnant women with gestational diabetes admitted to the hospital were selected as the observation group. Eighty pregnant women with non-diabetic pregnancy in the same period were selected as control group. The effects of pregnancy outcome and high risk factors on pregnant women and fetus outcome were observed. Results The fasting blood glucose and triglyceride in observation group were significantly higher than those in control group (P <0.01). The preterm birth rate, preeclampsia, pregnancy outcome of the giant fetus in the observation group were significantly different from those in the control group (P <0.05). The regression analysis showed that the risk factors of gestational diabetes had a certain impact on the outcome of pregnant women and fetuses. The main influencing factors were fasting blood glucose (FPG), triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL- C), high-density lipoprotein cholesterol (HDL-C), free fatty acid (FFA). Conclusion Gestational diabetes has a greater impact on the outcome of pregnant women and fetuses, to strengthen the control of gestational diabetes, reducing its impact on pregnancy outcomes.