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乳腺外来源的转移性乳腺癌在所有乳腺癌中所占比例较低,约为0.5%~1.2%,胃印戒细胞癌转移至乳腺更为罕见。本文报道了一例由胃印戒细胞癌转移至乳腺的女性患者,结合相关文献回顾,探讨并总结转移性乳腺癌与原发性乳腺癌在发病机制、临床表现、影像学特点及病理组织和免疫组化中的不同点。本报道旨在提示临床医师在乳腺肿瘤的诊断中,应详细结合患者病史,考虑到乳腺外转移可能,结合病理结果及免疫组化等手段以明确诊断,早期开展后续治疗。此外,随着循环肿瘤细胞和DNA技术的不断发展,对转移性乳腺癌机制的研究更加深入,可能会为此类疾病提供更好的治疗方案。
Metastatic breast cancer of extramammary origin in all breast cancer accounts for a relatively low proportion of about 0.5% to 1.2%, and metastasis of the signet ring cell carcinoma to the breast is more rare. In this paper, we report a case of female patients with gastric signet-ring cell carcinoma transferred to the breast. In combination with relevant literatures, the pathogenesis, clinical manifestations, imaging features, histopathology and immunity of metastatic breast cancer and primary breast cancer were discussed and summarized Differences in grouping. This report aims to prompt clinicians in the diagnosis of breast tumors should be combined with the patient’s history in detail, taking into account the possibility of extramammary metastasis, combined with pathological findings and immunohistochemistry and other means to confirm the diagnosis early carry out follow-up treatment. In addition, as circulating tumor cells and DNA technologies continue to evolve, more research into metastatic breast cancer mechanisms may provide better treatment options for these diseases.