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血液系统疾患如贫血(包括溶血性尿毒症)、血小板减少性紫癜、镰状细胞病、良性原发性高球蛋白血症等均可产生肾损害。本文主要将临床较常见的多发性骨髓瘤、淋巴瘤和白血病三种恶性血液病引起的肾损害作一叙述。一、多发性骨髓瘤的肾损害多发性骨髓瘤是浆细胞异常增生的恶性肿瘤。骨髓内有大量异常浆细胞增殖,引起骨骼疼痛和破坏、造血功能障碍(贫血、出血),血清和(或)尿中出现异常的单株免疫球蛋白和(或)免疫球蚤白的轻链(凝溶蛋白)。
Hematological disorders such as anemia (including hemolytic uremic disease), thrombocytopenic purpura, sickle cell disease, benign primary hypergammaglobulinemia, etc. can produce kidney damage. This article will be the more common clinical multiple myeloma, lymphoma and leukemia caused by three kinds of hematological malignancies made a narrative. First, multiple myeloma, renal damage Multiple myeloma is an abnormal proliferation of plasma cells in malignant tumors. There are a large number of abnormal plasma cells in the bone marrow proliferation, causing bone pain and destruction, hematopoietic disorders (anemia, bleeding), abnormal serum and / or urine monoclonal immunoglobulin and / or immunoglobulin white light chain (Streptavidin).