,Effects of intrinsic and extrinsic noises on transposons kinetics

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The absolute concentration robustness (ACR) steady state of a biochemical system can protect against changing a large concentration of the system’s components.In this paper,a minimal model of autonomous-nonautonomous transposons driven by intrinsic and extrinsic noises is investigated.The effects of intrinsic and extrinsic noises on ACR steady state of the transposons kinetics are studied by numerical simulations.It is found that the predator-prey-like oscillations around the ACR steady state are induced by the intrinsic or extrinsic noises.Comparing with the case of intrinsic noises,the extrinsic noises can inhibit the amplitude of oscillations of transposon kinetics.To characterize the predator-prey-like oscillations,we calculate the probability distributions and the normalized correlation functions of a system in the stability domain.With the increasing of noise intensity,the peak of the probability distribution is shifted from the ACR steady state to the trivial steady state.The normalized autocorrelation and cross-correlation functions indicate that the state of the predator-prey oscillator is transmitted to 50 successive generations at least.
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