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RNA和蛋白质在生物体中共同肩负着基因的表达和调控,在生命活动中具有重要作用。RNA干扰(RNAi)技术是存在于真核生物体内的一种阻断外源基因表达的自我防御体系,是由双链RNA介导的使与其互补的具有同源序列的单链RNA进行特异性的降解。主要概述RNAi技术的干涉机制及其在妇科肿瘤领域中的应用进展。
RNA and protein share the same gene expression and regulation in the organism and play an important role in the life activities. RNA interference (RNAi) technology is a self-defense system that blocks the expression of foreign genes in eukaryotes. It is mediated by double-stranded RNA to make its complementary single-stranded RNA with homologous sequences specific Degradation. The main overview RNAi interference mechanism and its application in the field of gynecologic oncology.