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异丙肾上腺素是β-肾上腺素能受体兴奋剂中活性最强的药物之一,对β_1和β_2受体均有很强兴奋作用。临床上广泛用于休克、房室传导阻滞、阿-斯综合征、心跳骤停和支气管痉挛的治疗。目前认为其作用系通过环磷酸腺甙(cAMP)在细胞水平上完成。虽然Lockett等自交感神经刺激后的肾上腺和肺静脉血液中提取到了异丙肾上腺素,并指出可能是体内介质之一,但迄今尚未被公认。一、副作用异丙肾上腺素的副作用已报道的有心悸、头晕、头痛、晕厥、心前区疼痛、食欲不振、口干、皮肤潮红、震颤、无力、出汗、耳鸣、失眠、神经质等。本品舌下含化时,除对敏感患者可引起恶心、呕吐外,
Isoprenaline is one of the most potent beta-adrenergic agonists and has a strong stimulatory effect on beta 1 and beta 2 receptors. Clinically widely used in shock, atrioventricular block, Als-Syndrome, cardiac arrest and bronchospasm treatment. It is currently thought that its action is accomplished at the cellular level by cAMP. Although isoprenaline has been extracted from the blood of the adrenal and pulmonary veins after sympathetic nerve stimulation by Lockett et al. And it has been pointed out that it may be one of the mediators in the body, it has not been recognized as yet. Side effects Isoproterenal side effects have been reported palpitations, dizziness, headache, fainting, precordial pain, loss of appetite, dry mouth, skin flushing, tremor, weakness, sweating, tinnitus, insomnia, nervousness and so on. This product contains sublingual, in addition to sensitive patients can cause nausea, vomiting,