论文部分内容阅读
目的:探讨辛伐他汀药理作用及临床应用。方法:选取2015年3月至2016年3月在我院门诊接受治疗的200例血脂异常患者为研究对象,所有患者均采用辛伐他汀治疗,对其临床效果进行观察,并对辛伐他汀的药理特点、药力作用以及常见的不良反应进行总结分析。结果:本文200例患者中,高血脂患者的治疗总有效率为95%,心绞痛患者的治疗总有效率为90%,冠心病患者的治疗总有效率为98%,2型糖尿病合并血脂异常的患者治疗总有效率为90%。结论:辛伐他汀是土曲霉发酵产物的合成衍生物,不仅能有效的控制血液中胆固醇的含量,预防心血管疾病,而且具有疗效确切、服用方便、毒副作用小等优点,临床上常用于治疗高胆固醇血症、冠心病、心绞痛等疾病。
Objective: To investigate the pharmacological effects of simvastatin and its clinical application. Methods: From March 2015 to March 2016 in our hospital for treatment of 200 cases of dyslipidemia patients were studied, all patients were treated with simvastatin, its clinical effect was observed, and simvastatin Pharmacological characteristics, pharmacological effects and common adverse reactions were analyzed. Results: Of the 200 patients in this study, the total effective rate was 95% in patients with hyperlipidemia, 90% in patients with angina pectoris, 98% in patients with coronary heart disease, and in type 2 diabetes with dyslipidemia The total effective rate of patients treated 90%. Conclusion: Simvastatin is a synthetic derivative of Aspergillus terreus fermentation products, not only can effectively control blood cholesterol levels, prevent cardiovascular disease, and has the exact effect, easy to take, the advantages of small side effects, clinically used in the treatment of Hypercholesterolemia, coronary heart disease, angina pectoris and other diseases.