本病为侵犯耳鼻喉、气管、支气管、诸多关节软骨系统的稀少而原因不明性炎症性疾病。往往伴有眼球各部炎症、内耳损害。 Jalesch—wartenhorst于1923年首先报导一例34岁的啤酒酿造者,此后病例报告增多,直到Bean的总论发表后才引起人们注意。1960年Pearson报导12例(其中有文献10例),从此报告的病例急速增加。 The disease is infringement ear, nose and throat, trachea, bronchi, many articular cartilage system sparse and unexplained inflammatory disease. Often accompanied by inflammation of the eye department, damage to the inner ear. Jalesch-wartenhorst first reported a 34-year-old brewer in 1923, and since then has seen an increase in the number of case reports, until the general introduction of the bean was made public. Pearson reported 12 cases in 1960 (of which 10 were included in the literature), and the number of reported cases increased rapidly.