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目的:观察纳洛酮治疗早产儿原发性呼吸暂停的疗效。方法:收集本院新生儿护理抢救中心2010年6月-2012年6月收治的72例早产儿,随机分为治疗组36例,对照组36例,对照组采取常规治疗,治疗组在常规治疗的基础上加用纳洛酮治疗。结果:治疗组显效率(69.4%)及总有效率(88.9%)均高于对照组,P<0.01。结论:纳洛酮针对病因治疗,对早产儿呼吸暂停有治疗和预防双重作用,早产儿呼吸暂停值得应用纳洛酮。
Objective: To observe the effect of naloxone on premature infants with primary apnea. Methods: Seventy-two premature infants who were admitted to Neonatal Nursing Center of our hospital from June 2010 to June 2012 were randomly divided into treatment group (36 cases) and control group (36 cases). The control group received routine treatment and the treatment group received conventional treatment Based on the addition of naloxone treatment. Results: The effective rate (69.4%) and total effective rate (88.9%) in the treatment group were significantly higher than those in the control group (P <0.01). CONCLUSIONS: Naloxone is the treatment of etiology and plays a dual role in the treatment and prevention of apnea in preterm infants. Naloxone should be used in premature infants with apnea.