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目的探讨慢性溃疡性结肠炎的临床疗效。方法对我科4年来确诊的慢性溃疡性结肠炎住院患者50例临床资料进行回顾性分析。结果50例患者内镜下表现为19例黏膜呈多发性浅溃疡,21例黏膜呈弥漫性充血水肿、颗粒状,10例附有血性分泌物,假性息肉形成。病理观察所有患者均表现为隐窝脓肿、浅表溃疡及杯状细胞减少,固有膜内淋巴、浆细胞和单核细胞为主的弥漫性炎症细胞浸润。结论慢性溃疡性结肠炎的主要临床表现为腹痛、腹泻及黏液脓血便,给予针对性综合治疗、个体化治疗和药物治疗原则,其治愈成功率较高。
Objective To investigate the clinical efficacy of chronic ulcerative colitis. Methods The clinical data of 50 patients with chronic ulcerative colitis admitted to our hospital in 4 years were retrospectively analyzed. Results The endoscopic findings of 50 patients were multiple ulceration in 19 cases. The mucosa of 21 patients showed diffuse congestion, edema and granuloma, with 10 cases of bloody discharge and pseudo polyp formation. Pathological observation of all patients showed crypt abscess, superficial ulcers and goblet cells decreased, inherent membrane lymphatic, plasma cells and monocytes predominant diffuse inflammatory cell infiltration. Conclusion The main clinical manifestations of chronic ulcerative colitis are abdominal pain, diarrhea and mucous pus and blood stool. Given the principles of comprehensive treatment, individualized treatment and drug treatment, the cure rate of chronic ulcerative colitis is high.