从高度复杂的生物体系中识别、鉴定和分离药物受体是当前分子药理学中最艰巨问题之一。已知大多数药物受体在膜上,大多数激素受体也在膜上,少数(如子宫雌激素受体)在细胞浆内。如果要将受体从膜上分离,必须借助去垢剂等方法使之溶解释放。但大多数受体从膜上释放后,受体对特定药物或激素结合的能 Identifying, identifying and isolating drug receptors from highly complex biological systems is one of the most difficult problems in current molecular pharmacology. Most drug receptors are known to be on the membrane, and most hormone receptors are also on the membrane, with a few (such as uterine estrogen receptors) in the cytoplasm. If you want to separate the receptor from the membrane, you must make use of detergent and other methods to dissolve the release. However, after most receptors are released from the membrane, the receptor can bind to a particular drug or hormone