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目的 探讨高龄人群结肠癌普查的可行性和必要性。方法 对1638 名无症状老年人(60 - 90 岁) 连续11年每年行粪便序贯隐血筛检(SFOBT) 一次,SFOBT 阳性者予全结肠肠镜检查。结果 每年普查率约为80 % ,计1310 人。共检出大肠癌12 例,大肠腺瘤130 例,其年发病率分别为66-60/10 万及72-15/10 万。在11 年连续筛检的个体中,检出大肠癌3 例。未连续检查的个体中,检出大肠癌9 例。130 例大肠腺瘤均于结肠镜下切除,随访11 年无1 例癌变。结论 高龄人群是大肠癌的高危人群,大肠癌普查可提高可愈癌和腺瘤的检出。因此提高筛检的敏感性和依从性是可治愈大肠癌检出的关键因素。切除大肠腺瘤可预防大肠癌的发生
Objective To investigate the feasibility and necessity of colon cancer screening in elderly population. Methods A total of 1638 asymptomatic seniors (60-90 years) underwent sequential stool screening (SFOBT) once a year for 11 consecutive years, and patients with positive SFOBT were given colonoscopy. Results The annual census rate is about 80%, accounting for 1310 people. Colorectal cancer was detected in 12 cases, 130 cases of colorectal adenoma, the annual incidence rates were 66-60 / 100,000 and 72-15 / 100,000. In 11 consecutive screening of individuals, detected in 3 cases of colorectal cancer. Among the individuals who did not examine continuously, 9 cases of colorectal cancer were detected. 130 cases of colorectal adenomas were resected in colonoscopy, no case of cancer in 11 years follow-up. Conclusion The elderly population is a high risk group of colorectal cancer, and the screening of colorectal cancer can improve the detection of recoverable cancer and adenoma. Therefore, increasing the sensitivity and compliance of screening is a key factor in the detection of colorectal cancer. Colorectal adenoma removal can prevent the occurrence of colorectal cancer