肝纤维化是各种慢性肝病进展过程中由于肝内纤维组织生成与降解失衡,过多的胶原在肝内沉积所致,是肝硬化的前期病变,如何控制和逆转肝纤维化将最终决定患者病情的转归[1]。我们采取干扰素-α联合肝康Ⅱ治疗乙型肝炎肝纤维化,治疗前后观察患者血清肝纤维化指标变化,报告如下。1 Liver fibrosis is a variety of chronic liver disease progression due to the imbalance between the formation and degradation of intrahepatic fibrosis, excessive deposition of collagen in the liver, is a pre-cirrhosis, how to control and reverse the liver fibrosis will ultimately determine the patient The outcome of the disease [1]. We take interferon-α combined liver and liver Ⅱ treatment of hepatitis B liver fibrosis, before and after treatment in patients with changes in serum markers of liver fibrosis, the report is as follows. 1