孢子丝菌病常为职业性,最常见于农民、园丁、花匠及苗圃工。很多个体在患该病后仍继续从事同一职业。由于感染后不发生持久的免疫,因此,发生第二次感染是可信的。既往仅报告过一例第二次感染申克氏孢子丝菌病,本文报告两例。病例一,52岁、男性、白种人、药剂师,于右中指甲根部长一红色结节已数月。后左腕背部、左前臂及肘部也发生几个结节,无溃疡、淋巴腺不大。患者曾砍木材及常在玫瑰花灌木丛附近劳动,皮损 Sporotrichosis is often occupational and most commonly found among farmers, gardeners, gardeners and nurseries. Many individuals continue to work in the same occupation after suffering from the disease. Since there is no lasting immunity after infection, a second infection is believed to be credible. In the past, only one case of second-case conidiosporeosis was reported, two cases were reported in this paper. Case 1. A 52-year-old man, a Caucasian, a pharmacist, had a red nodule on the nail of the right middle finger for a few months. After the left wrist back, left forearm and elbows also occur in several nodules, no ulcers, lymph nodes is not large. Patients have cut wood and often work in the rose bush, skin lesions