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目的探讨垂体腺瘤术后并发尿崩症和低钠血症的临床特点及处理方法,以及时发现和对症处理,提高垂体腺瘤的术后治疗水平。方法回顾性总结近10年来收治的305例垂体腺瘤手术患者的临床资料,统计分析出现水钠代谢紊乱的发生和治疗情况。结果在305例患者中,有69例术后出现尿崩症,其中一半的患者在一周内得到控制,90%的患者在术后3个月内恢复。42例术后出现低钠血症,多数患者1周内恢复正常。结论术后每日检测血钠并观察尿量变化并根据其变化进行正确处理,与手术本身具有同样的重要性,是患者获得良好疗效的关键。
Objective To investigate the clinical features and treatment of postoperative diabetes insipidus and hyponatremia in pituitary adenomas and to find out and symptomatically treat them in time to improve the postoperative treatment of pituitary adenomas. Methods The clinical data of 305 cases of pituitary adenoma treated in recent 10 years were retrospectively reviewed. The occurrence and treatment of water-sodium metabolic disorders were statistically analyzed. RESULTS Of the 305 patients, 69 had postoperative diabetes insipidus, and half of them were controlled within one week and 90% recovered within 3 months of surgery. 42 cases of hyponatremia after surgery, most patients returned to normal within 1 week. Conclusions Daily postoperative serum sodium and urine output changes observed and correctly adjusted according to their changes, and surgery itself has the same importance, is the key to good effect in patients.