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测定IgM族特异性抗体在区别近期感染与既往感染上是有用的。作者用反向酶联免疫吸附技术,研究在确诊的急性与慢性乙型肝炎病例中IgM抗-HBc的出现与持续时间,探索在下列临床问题中IgM的诊断价值:(1)检出HBsAg阴性的乙型肝炎病例;(2)鉴别HBsAg阳性病人的急性感染或慢性感染;(3)无症状献血员中HBV感染的频率。58例入院时HBsAg阳性的急性肝炎患
Determining IgM family-specific antibodies is useful in distinguishing between recent infections and previous infections. The authors used reverse enzyme-linked immunosorbent assay to study the presence and duration of IgM anti-HBc in confirmed acute and chronic hepatitis B cases and to explore the diagnostic value of IgM in the following clinical issues: (1) detection of negative HBsAg Of hepatitis B cases; (2) identification of acute or chronic HBsAg-positive patients; and (3) frequency of HBV infection in asymptomatic blood donors. 58 cases of HBsAg-positive acute hepatitis at admission