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目的：分析口腔颌面部鳞癌患者的手术切除方法和面部修复重建效果。方法：选取我院口腔颌面外科收治的口腔颌面部鳞癌患者36例，均在我院接受手术治疗以及修复重建。结果：本组患者中，随访期间33例患者手术后无复发以及转移的情况发生，且术后患者口腔以及颌面部恢复情况良好，有1例上颌窦鳞癌患者在术后2年复发，肿瘤细胞转移至患者颅内导致患者死亡，1例口底鳞癌患者术后3年全身骨性转移导致患者死亡，1例患者术后2年出现脑出血及相关并发症对症治疗无效后患者因脏器功能衰竭死亡。修复重建患者中，2例胸大肌肌皮瓣修复后出现边缘性的小部分组织坏死，形成口腔瘘，其他患者无相关并发症发生。结论：外科手术治疗是现临床上治疗口腔颌面部鳞癌患者的主要治疗方法，而患者术后进行修复重建有利于提高患者的生活质量及其对抵抗病魔的自信心。“,”Objective To analysis of oral and maxillofacial squamous carcinoma resection method and the effect of facial reconstruction.Methods To choose our oral and maxillofacial surgery were 36 patients with oral and maxillofacial squamous carcinoma, both in the hospital surgery treatment and rehabilitation.Results This group of patients, 33 cases during the follow-up period after surgery in patients with no recurrence and metastasis, and postoperative patients with oral and maxillofacial recovering well, 1 cases of maxillary sinus squamous carcinoma recurrence 2 years after surgery, patients with metastasis to the patients with intracranial tumor cells leads to death, 1 case of 3 years postoperatively in patients with oral squamous cell carcinomas patients with osseous metastasis lead to death, 1 case of patients with postoperative 2 years in patients with cerebral hemorrhage and related complications after symptomatic treatment is invalid die in viscera function failure. In patients with reconstruction, 2 cases of pectoralis major myocutaneous flap to repair after the borderline of a small number of tissue necrosis, oral fistula formation, other patients without associated complications.Conclusion Surgical treatment is now the clinical treatment of patients with oral and maxillofacial squamous cell carcinomas of the main treatment, and patients with postoperative restoration reconstruction to improve the quality of life of patients with confidence and its resistance to the disease.