目的:探讨n 18F-脱氧葡萄糖(FDG)PET/CT联合CT三期动态增强扫描在诊断肝上皮样血管内皮瘤(HEH)中的价值。n 方法:回顾性分析2013年11月至2018年11月青岛市中心医院的6例[男2例、女4例，年龄(41.0±5.6)岁]经穿刺病理证实的HEH患者的影像学表现。6例均行n 18F-FDG PET/CT双时相及同机CT三期动态增强扫描，分析患者肝病变的n 18F-FDG PET/CT影像特点和CT强化特征。n 结果:6例HEH患者均为多发病灶，共30个病灶，其中16.7%(5/30)有包膜回缩征，33.3%(10/30)有靶征，13.3%(4/30)有“棒棒糖征”。CT增强扫描时病灶呈3种强化方式：轻度渐进性强化、延迟明显强化以及门脉期出现黑靶征、白靶征。30个病灶中20个(66.7%)表现为n 18F-FDG摄取程度高于肝实质，常规显像最大标准摄取值(SUVn max)为4.18±0.64，延迟显像SUVn max为4.23±0.70，滞留指数为0.65(-1.88，4.60)；10个(33.3%)表现为n 18F-FDG摄取与肝实质相似，常规显像SUVn max为2.75±0.52，延迟显像SUVn max为2.78±0.55。延迟显像后22个病灶SUVn max升高，8个病灶SUVn max降低。在n 18F-FDG代谢不均匀的病灶中，代谢相对较高的部位也是CT增强峰值较高的部位；代谢较均匀病灶的CT增强方式也比较均匀。2例患者同时伴有双肺转移。n 结论:18F-FDG PET/CT双时相显像联合同机CT三期动态增强扫描有助于HEH的准确诊断，同时可显示肝外转移灶。n “,”Objective:To explore the value of n 18F-fluorodexyglucose (FDG) PET/CT combined with integrated contrast-enhanced CT on the diagnosis of hepatic epithelioid hemangioendothelioma(HEH).n Methods:Six patients (2 males, 4 females, age: (41.0±5.6) years) histopathologically confirmed to be HEH in Qingdao Central Hospital between November 2013 and November 2018 were retrospectively analyzed. All patients underwent n 18F-FDG PET/CT dual-phase imaging and three-phase dynamic enhanced scanning with integrated CT. Characteristics of n 18F-FDG PET/CT and contrast-enhanced CT images were classified and analyzed.n Results:All 6 patients had multi-lesions (30 lesions in total). The capsule retraction sign was found in 16.7% (5/30) lesions, target sign was found in 33.3% (10/30) lesions, and “ lollipop sign” was found in 13.3% (4/30) lesions. There were three ways of enhancement showed by CT: mild progressive enhancement, delayed enhancement, and black target sign/white target sign in the portal phase. Among the 30 lesions, 66.7% (20/30) had higher n 18F-FDG uptake than liver parenchyma, with maximum standardized uptake value (SUVn max) of 4.18±0.64 during routine imaging and 4.23±0.70 during delayed imaging, and the retention index was 0.65(-1.88, 4.60). The rest 33.3% (10/30) showed similar n 18F-FDG uptake to liver parenchyma, with SUVn max of 2.75±0.52 during routine imaging, and 2.78±0.55 during delayed imaging. The uptake of n 18F-FDG increased with time in 22 lesions and decreased in 8 lesions. In the metabolically heterogeneous lesions, the relatively high-metabolization site was also the site with higher peak enhancement; in the lesions with uniform metabolism, the CT enhancement was also uniform. Bilateral pulmonary metastases were found in 2/6 patients.n Conclusion:18F-FDG PET/CT dual-phase imaging combined with CT three-phase dynamic enhanced scanning is helpful in accurate diagnosis of HEH and could show extrahepatic metastases.n