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曾经有研究报告指出,置于压缩—减压下会增加血—脑屏障对有机染料及抗生素的渗透性.作者报告了由于海拔高度的减压引起的血—脑屏障机能和超微结构的变化.实验组免29只,对照组19只,经静脉注入2%台盼蓝(trypan blue)4毫升/公斤.有一些实验动物还注入辣根过氧化酶(horsetadish peroxidase),实验动物置于30000英尺(4.3磅/每平方英寸)高度45分钟,对照组动物仍留在陆地平面.所有动物于注射药物后90分钟处死,作大体和显微镜检查,以及光谱分析染色浓度检查、结果显示实验动物平均染色浓度
Previous studies have reported that exposure to compression-decompression increases the permeability of the blood-brain barrier to organic dyes and antibiotics, and the authors report changes in blood-brain barrier function and ultrastructure as a result of decompression at altitude 29 in the experimental group and 19 in the control group were injected intravenously with 2% trypan blue at a rate of 4 ml / kg. Some experimental animals were also injected with horsetadish peroxidase and the experimental animals were placed at 30000 Feet (4.3 pounds per square inch) at a height of 45 minutes, animals in the control group remained on land level All animals were sacrificed 90 minutes after injection of the drug for gross and microscopic examination, and spectral analysis of staining concentration showed that the average Dyeing concentration