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目的总结凯纷与曲马多在患儿扁桃体和腺样体手术的镇痛效果及不良反应。方法 2009年4月-2009年10月,将60例行扁桃体和腺样体摘除术患儿,随机分为A组(凯芬组)、B组(曲马多组)及C组(对照组)。A组于麻醉插管后手术开始前10min静注凯纷1mg/kg,B组静注曲马多1mg/kg,C组静注等量生理盐水。观察其拔管时间、苏醒期反应、恢复期疼痛评分、低血氧症的发生、恶心呕吐及术野区出血情况。结果 3组患儿的拔管时间、术后低氧血症的发生率均无统计学意义。监测治疗室(PACU)中A、B组患儿的苏醒期躁动发生率及疼痛评分明显低于C组(P<0.05),且A组无恶心呕吐发生,B、C组恶心呕吐的发生率分别为11.1%和5%。结论凯纷及曲马多用于小儿扁桃体和腺样体手术均可获得良好的镇痛及镇静效果,并减少了拔管期的躁动发生且不增加拔管时间及术后低血氧症。但凯纷组患儿没有恶心呕吐发生,更适用于小儿的扁桃体;腺样体;手术。
Objective To summarize the analgesic effects and adverse reactions of Triptych and Tramadol in children with tonsil and adenoid surgery. Methods From April 2009 to October 2009, 60 children undergoing tonsillectomy and adenoidctomy were randomly divided into group A (Caffeine group), group B (tramadol group) and group C (control group ). Group A was anesthetized 10min before intubation after surgery Kai Kai 1kg / kg, group B intravenous tramadol 1mg / kg, group C intravenous injection of equal volume of saline. The extubation time, recovery reaction, recovery pain score, the incidence of hypoxemia, nausea and vomiting and bleeding in operation area were observed. Results The time of extubation and the incidence of postoperative hypoxemia in 3 groups were not statistically significant. The incidence of recumbent agitation and pain scores in group A and group B in PACU were significantly lower than those in group C (P <0.05), and no incidence of nausea and vomiting was found in group A, and the incidence of nausea and vomiting in group B and C Respectively 11.1% and 5%. Conclusions Triptolide and tramadol can be used in children with tonsil and adenoid surgery can achieve good analgesic and sedative effects and reduce extubation agitation without increasing extubation time and postoperative hypoxemia. However, Kai Fun group no nausea and vomiting occurred in children, more suitable for pediatric tonsils; adenoids; surgery.