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目的:总结小儿畸胎瘤的临床特点及诊断、治疗经验。方法:对89例小儿畸胎瘤患者的临床资料进行回顾性分析。结果:本组89例小儿畸胎瘤多发生于骶尾部、性腺和腹膜后,分别为28例(31%)、27例(30%)和23例(26%);其中良性畸胎瘤70例(79%)血清甲胎蛋白升高13例(19%);恶性畸胎瘤19例(21%),甲胎蛋白升高13例(68%)。本组全部行手术治疗,恶性者术后加化学治疗和(或)介入治疗;恶性病例随访3年,复发6例,死亡3例,病情稳定10例。结论:病理检查是诊断小儿畸胎瘤的主要方法,血清甲胎蛋白检查是判断良、恶性畸胎瘤的一个客观指标。小儿畸胎瘤一旦确诊应手术切除。
Objective: To summarize the clinical features, diagnosis and treatment of pediatric teratoma. Methods: The clinical data of 89 cases of pediatric teratoma were analyzed retrospectively. Results: 89 cases of pediatric teratoma occurred in the sacrococcygeal, gonads and retroperitoneum, which were 28 (31%), 27 (30%) and 23 (26%) respectively. Among them, benign teratoma 70 Serum AFP levels were elevated in 13 (19%) cases; malignant teratoma in 19 (21%) and alpha-fetoprotein in 13 (68%) cases. Surgical treatment of malignant patients, postoperative chemotherapy and (or) interventional treatment; malignant cases were followed up for 3 years, 6 cases of recurrence, 3 died, 10 cases of stable. Conclusion: Pathological examination is the main method to diagnose pediatric teratoma. Serum alpha-fetoprotein test is an objective indicator to judge benign and malignant teratoma. Teratoma in children once diagnosed should be surgically removed.