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目的:本文试就STIR法对小儿贫血及白血病的骨髓改变的MRI诊断价值加以讨论。材料和方法:本组病例包括经骨穿检查的贫血患儿12例(缺铁性贫血3例,巨细胞贫血2例,再障贫血7例);白血病12例。同年龄对照组20例。扫描方法:STIR序列,TR=1500msec,TI=100msec,TE=30msec;部位:腰骶部及胸腰段椎体的矢状位。结果:正常组在STIR序列中骨髓信号为边缘高信号,中心低信号,中心低信号区随年龄的增加扩大和明显,是脂肪髓化的部位,边缘的高信号区为造血细胞存在部位。缺铁性贫血的3例和巨细胞贫血的2例均可见骨髓边缘的高信号区明显扩大,但仍保持正常的分布状态;再障贫血的7例出现骨髓边缘的高信号区消失,但1例骨髓低信号中可见星点状高信号,为残存的造血组织。12例白血病病例中10例可见骨髓信号明显升高且信号混杂,中心区亦可见高信号,失去了正常的分布;另2例化疗后的病例,骨髓信号虽高而不均,但中心部的低信号已见。结论:STIR法对小儿贫血及白血病骨髓改变的评价有意义
Objective: This article attempts to STIR method of pediatric anemia and bone marrow changes in leukemia MRI diagnostic value is discussed. Materials and Methods: This group of patients included 12 cases of children with anemia who had undergone bone penetrating examination (3 cases of iron deficiency anemia, 2 cases of giant cell anemia and 7 cases of aplastic anemia) and 12 cases of leukemia. The same age group of 20 cases. Scanning methods: STIR sequence, TR = 1500 msec, TI = 100 msec, TE = 30 msec; site: the sagittal position of lumbosacral and thoracolumbar vertebral body. Results: In the STIR sequence, the bone marrow signals of the normal group were marginal high signal and low center signal. The central low signal area was enlarged and obviously increased with age. The high signal area of the marginal area was the site of hematopoietic cells. 3 cases of iron deficiency anemia and 2 cases of giant cell anemia can be seen in the bone marrow marginal high signal area was significantly expanded, but still maintain the normal distribution; aplastic anemia in the bone marrow edge of the high signal area disappears, but 1 In cases of bone marrow low signal visible asteroid high signal, the remaining hematopoietic tissue. In 12 cases of leukemia, the bone marrow signal was significantly increased and the signal was mixed in 10 cases. The high signal was seen in the central area and the normal distribution was lost. In the other 2 cases after chemotherapy, the signal of the bone marrow was high and uneven, but in the central part Low signal has been seen. Conclusion: The STIR method is of value in the evaluation of pediatric anemia and leukemia bone marrow changes