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目的探讨无创机械通气对慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的临床疗效。方法对42例符合诊断标准的COPD合并Ⅱ型呼吸衰竭的患者给予无创机械通气(BiPAP)治疗,观察治疗前,上机后4h、24h、48h的动脉血气分析中的pH值、PaCO2、PaO2、SO2的变化。结果经过无创机械通气治疗后,患者临床症状有明显缓解,治疗后血气分析中的pH值、PaO2、SO2、PaCO2较治疗前有明显改善(P<0.05)。结论无创机械通气对COPD合并Ⅱ型呼吸衰竭患者的治疗效果显著,在临床上可推广应用。
Objective To investigate the clinical effect of noninvasive mechanical ventilation on chronic obstructive pulmonary disease (COPD) with type Ⅱ respiratory failure. Methods 42 cases of patients with COPD and type Ⅱ respiratory failure who met the diagnostic criteria were given BiPAP. The values of PaCO2, PaO2, PaO2, PaO2 and PaO2 in arterial blood gas analysis before treatment, 4 h, SO2 changes. Results After noninvasive mechanical ventilation, clinical symptoms were relieved. After treatment, the values of PaO2, SO2 and PaCO2 in blood gas analysis were significantly improved (P <0.05). Conclusion Noninvasive mechanical ventilation has significant therapeutic effect on patients with COPD complicated with type Ⅱ respiratory failure and can be popularized in clinic.