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目的:探讨低分子肝素治疗颅内静脉窦血栓形成(CVST)的临床疗效。方法:将70例CVST患者随机分为治疗组和对照组各35例。对照组采用常规治疗,治疗组在常规治疗的基础上加用低分子肝素。结果:治疗组痊愈20例,好转12例,总有效率为91.4%;对照组痊愈15例,好转7例,总有效率为62.9%。经统计学处理,治疗组总有效率明显高于对照组(P<0.01)。治疗组除注射部位有淤斑外,未见其他不良反应。结论:低分子肝素治疗CVST疗效确切,安全可靠。
Objective: To investigate the clinical effect of low molecular weight heparin in the treatment of intracranial venous sinus thrombosis (CVST). Methods: Seventy patients with CVST were randomly divided into treatment group and control group, 35 cases each. Control group with conventional treatment, the treatment group in the conventional treatment based on the use of low molecular weight heparin. Results: The treatment group recovered 20 cases, improved in 12 cases, the total effective rate was 91.4%; control group cured 15 cases, improved in 7 cases, the total effective rate was 62.9%. After statistical analysis, the total effective rate of the treatment group was significantly higher than that of the control group (P <0.01). In addition to the treatment group had plaque outside the injection site, no other adverse reactions. Conclusion: Low molecular weight heparin is effective and safe for the treatment of CVST.