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毒杀芬学名八氯莰烯,为有机氯杀虫剂。残效期较长,主要用于防治棉花虫害.我室曾对国产毒杀芬纯品(含氯量67.9％)的急性、蓄积性和亚急性毒性进行了研究,最小有作用剂量为216ppm,最大无作用剂量为36ppm,推算人的每日最大容许摄入量(ADI值)为0.036mg/kg体重/日。本文试图对国产毒杀芬的胚胎毒性作进一步研究,以期对其安全使用提出有关依据。本实验采用我院动物房繁殖的成年来交配过的“昆明种”小鼠,体重雄性34～52克,雌性27～43克,雄:雌按1:2交配,将孕鼠随机分为47.50(1/2LD_(50))、11.87(1/8LD_(60))及2.96(1/32
Poison killed Fen name octocrylene, organochlorine pesticides. The residual period is longer, mainly for the prevention and treatment of cotton pests and insects .In our laboratory, the acute, accumulative and sub-acute toxicities of domestic pure toxins (chlorine content 67.9%) were studied. The minimum effective dose was 216ppm, The no-effect dose was 36 ppm, and the human’s maximum allowable daily intake (ADI value) was 0.036 mg / kg body weight / day. This paper attempts to make further study on the toxic effects of domestic toxaphene in preparation for its safe use. In our experiment, the “Kunming” mice that had been mated in our hospital were 34-52 g in weight and 27-43 g in female. The male and the female were mated at 1: 2, and the pregnant rats were randomly divided into 47.50 (1/2 LD_ (50)), 11.87 (1/8 LD_ (60)) and 2.96 (1/32