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利眠宁是具有抗焦虑特性的第一个苯并二氮革药物。它的发现引人入胜,并表明好运气仍是新药发现的一个重要因素。五十年代期间,美国罗士(Roche)药厂实验室开始了一项寻找新的安定剂的课题研究。选择苯并二氮革化学基团作为研究,部分原因是该研究小组的领导三十年代早期在波兰已做
Chlordiazepoxide is the first benzodiazepine drug to have anti-anxiety properties. Its discovery is fascinating and shows that good luck is still an important factor in the discovery of new drugs. During the 1950s, Roche Laboratories started a research project to find new stabilizers. The choice of benzodiazepine chemistry as part of the study was partly due to the leadership of the research team having done in Poland in the early 1930’s