喉癌是头颈部常见的恶性肿瘤，研究表明，人乳头瘤病毒１６型、１８型（ＨＰＶ１６、１８）感染及抑癌基因ｐ５３突变都在喉癌的发生发展中起作用，但二者到底有什么关系呢？为此，我们应用聚合酶链反应（ＰＣＲ）和限制性片段长度多态性（ＲＦＬＰ）分析技术对喉鳞癌组织中Ｈ Laryngeal cancer is a common malignant tumor in head and neck. Studies have shown that human papillomavirus type 16 and type 18 (HPV16,18) infection and tumor suppressor gene p53 mutations play a role in the occurrence and development of laryngeal cancer, but in the end What is the relationship? To this end, we applied polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) analysis of laryngeal squamous cell carcinoma tissue H