胎儿甲状腺功能减退 (胎儿甲减 )对胎婴儿有很多不利影响 ,如智力、精神运动能力障碍或减退 ,骨骼发育不良 ,严重时可引起克汀病。胎儿甲减的病因主要有先天性甲状腺功能减退 (CH)、药物性甲减、缺碘和母亲患自身免疫性甲状腺疾病 (AITD)。脐静脉血穿刺 (有经验的医师在 2 5～ 2 7周时穿刺是可行的 ,不良反应 <1%)测得TSH升高、FT4降低 ,超声检查示胎儿甲肿、发育迟缓、畸形 ,胎儿心动过缓可以诊断胎儿甲减[1～ 3 ] 。 Fetal hypothyroidism (Fetal hypothyroidism) has a lot of adverse effects on the baby fetus, such as mental retardation or mental decline, poor bone development, can cause cretinism in severe cases. The main causes of fetal hypothyroidism are congenital hypothyroidism (CH), drug hypothyroidism, iodine deficiency and maternal autoimmune thyroid disease (AITD). Umbilical cord blood puncture (experienced physicians punctured at 25-27 weeks is feasible, adverse reactions <1%) measured elevated TSH, FT4 decreased, ultrasound showed fetal gnarlosis, stunting, deformity, fetal Bradycardia can diagnose fetal hypothyroidism [1 ~ 3].