Generation of a monkey with MECP2 mutations by TALEN-based gene targeting

来源 :神经科学通报(英文版) | 被引量 : 0次 | 上传用户:cox_726
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
其他文献
Although extensively studied,the exact role of sleep in learning and memory is still not very clear.Sleep deprivation has been most frequently used to explore the effects of sleep on learning and memory,but the results from such studies are inevitably com
Adult neural stem cells (aNSCs) primarily exist in two regions:the subventricular zone (SVZ) of the lateral ventricle (LV) and the subgranular zone (SGZ) in the hippocampal dentate gyrus (DG) [1].It has been revealed that aNSCs in the SVZ (called type B c
期刊
After brachial plexus avulsion (BPA),microglia induce inflammation,initiating and maintaining neuropathic pain.EZH2 (enhancer of zeste homolog 2) has been implicated in inflammation and neuropathic pain,but the mechanisms by which it regulates neuropathic
Background:The Historical Importance of Studies of Human Brain in Dementia Research rnThe collection of brain and related tissue has a long history [1].In terms of dementia,a more systematic examination of the relationship between brain pathology and clin
期刊
Recently,Khayachi et al.[1] showed that fragile X mental retardation protein (FMRP) is an active substrate of the small ubiquitin-like modifier (SUMO) pathway in neurons.FMRP SUMOylation is induced by the activation of metabotropic glutamate receptors (mG
期刊
Introduction rnRecurrent complex visual hallucinations are a core clinical feature of dementia with Lewy bodies (DLB) and are typically well-formed,often consisting of figures,such as people or animals [1].Despite the profound impact upon patients and car
期刊
A previous functional magnetic resonance imaging study reported evidence for parallel memory traces in the hippocampus:a controlled match signal detecting matches to internally-generated goal states and an automatic mismatch signal identifying unpredicted
Neuropathic pain is a chronic debilitating symptom characterized by spontaneous pain and mechanical allodynia.It occurs in distinct forms,including brushevoked dynamic and filament-evoked punctate mechanical allodynia.Potassium channel 2.1 (Kir2.1),which