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目的探讨2010-2014年浙江省台州市甲状腺癌发病和死亡趋势,为制定台州市甲状腺癌防治策略提供参考依据。方法根据2010-2014年台州市甲状腺癌发病和死亡监测数据计算年龄别性别发病率和死亡率及其标化率。采用Joinpoint Regression Program 4.2软件估算年度变化百分比(APC),分析2010-2014年甲状腺癌发病率和死亡率的变化趋势。结果 2010-2014年台州市甲状腺癌粗发病率为15.28/10万,标化率为14.77/10万,甲状腺癌粗死亡率为0.51/10万,标化率为0.46/10万,分别占恶性肿瘤发病和死亡构成的5.29%和0.31%;女性发病率是男性的3.33倍,差异有统计学意义(χ2=334.43,P<0.01),女性死亡率是男性的1.34倍,差异无统计学意义(χ2=2.87,P=0.090)。甲状腺癌发病率在20~24岁组快速升高,50~54岁组达到高峰(38.02/10万),各年龄组甲状腺癌发病率均为女性高于男性。甲状腺癌死亡率从55~59岁组(0.74/10万)开始快速上升,在85岁以上组达到最高峰(7.14/10万),绝大多数年龄组女性死亡率高于男性。2010-2014年台州市甲状腺癌发病率和死亡率均呈上升趋势,其中发病率增长了124.35%,APC为28.5%;死亡率增长了17.44%,APC为6.7%。结论台州市甲状腺癌发病率和死亡率均呈上升趋势,需积极寻找相关危险因素,针对重点人群开展综合防治干预。
Objective To investigate the incidence and mortality of thyroid cancer in Taizhou City, Zhejiang Province during 2010-2014, and provide reference for the prevention and treatment of thyroid cancer in Taizhou City. Methods According to the data of incidence and mortality of thyroid cancer in Taizhou from 2010 to 2014, the incidence and mortality of age-specific sex and its standardization rate were calculated. The annual percentage change (APC) was estimated using Joinpoint Regression Program 4.2 software to analyze the trend of the incidence and mortality of thyroid cancer from 2010 to 2014. Results In 2010-2014, the incidence of thyroid cancer in Taizhou was 15.28 / lakh, the standardization rate was 14.77 / lakh, the crude death rate of thyroid cancer was 0.51 / lakh, the standardization rate was 0.46 / lakh, accounting for malignant Cancer incidence and mortality accounted for 5.29% and 0.31%, respectively. The incidence rate of women was 3.33 times higher than that of men (χ2 = 334.43, P <0.01). The mortality rate of females was 1.34 times that of males, with no significant difference (χ2 = 2.87, P = 0.090). The incidence of thyroid cancer in 20 to 24 years old group increased rapidly, 50 to 54 years old group reached the peak (38.02 / 100000), the incidence of thyroid cancer in all age groups were higher than men. The mortality of thyroid cancer increased rapidly from 55 to 59 years old (0.74 / 100000), and reached its peak (7.14 / 100000) in the group over 85 years old. The mortality rate of female in most age group was higher than that of male. The morbidity and mortality of thyroid cancer in Taizhou from 2010 to 2014 showed an upward trend. The incidence of thyroid cancer increased by 124.35%, APC was 28.5%, mortality increased by 17.44% and APC was 6.7%. Conclusion The morbidity and mortality of thyroid cancer in Taizhou are on the rise. Actively looking for relevant risk factors and conducting comprehensive prevention and treatment intervention for key populations.