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本实验选用中药枸杞有效成分和大蒜油,腹腔注射联合作用于U14腹水型宫颈癌小鼠后.对癌细胞细胞化学的影响进行了分析。结果显示,联合用药组小鼠癌细胞减少,细胞受到不同程度的破坏,细胞内DNA、RNA含量降低,ACPase、a-ANAE、ATPase、SDH、G-6-PDH活性减弱,含量降低,与对照组形成明显对比,P<0.01.与单独用药组比较,亦P<0.01。揭示联合用药可直接作用于癌细胞,抑制癌细胞遗传物质DNA合成和RNA转录.阻碍了癌细胞正常代谢,加速癌细胞死亡。
In this experiment, the active ingredients of Chinese wolfberry and garlic oil were injected intraperitoneally in combination with U14 ascites-type cervical cancer mice. The effects of cancer cell cytochemistry were analyzed. The results showed that the combination of drugs reduced the number of cancer cells, cells were damaged to varying degrees, DNA, RNA content decreased, ACPase, a-ANAE, ATPase, SDH, G-6-PDH activity decreased, Group formed a clear contrast, P <0.01. Compared with the drug alone group, also P <0.01. Reveal that the combination therapy can directly act on cancer cells and inhibit DNA synthesis and RNA transcription of cancer cell genetic material. Hinder the normal metabolism of cancer cells, accelerate cancer cell death.