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目的:研究痰热清注射液与炎琥宁联用治疗HFMD(hand-foot-and-mouth disease)患儿的疗效及安全性。方法:选取确诊和诊治的HFMD患儿68例为研究对象,将其随机分成观察组和对照组(每组34例,对照组患者给予利巴韦林静脉滴注治疗,观察组患者给予痰热清与炎琥宁联用治疗,对比两组治疗后的疗效。结果:经治疗后,观察组患儿退热时间、疱疹消退时间、口腔溃疡愈合时间、住院时间等均短于对照组(P<0.05)。结论:痰热清与炎琥宁联用治疗HFMD患儿,其疗效较为确切,二药具有协同药效,可抑制病毒复制,疗效优于利巴韦林。
Objective: To study the efficacy and safety of Tanreqing Injection combined with Yanhuning in the treatment of children with HFMD (hand-foot-and-mouth disease). Methods: A total of 68 children with HFMD diagnosed and diagnosed as HFMD were enrolled in this study. They were randomly divided into observation group and control group (34 cases in each group). Patients in control group were treated with intravenous ribavirin, while patients in observation group were given phlegm-dampness Qing and Yanhuning combined treatment, the curative effect of the two groups were compared.Results: After treatment, the observation group of children with antipyretic time, herpes subsided time, oral ulcer healing time, hospitalization time were shorter than the control group (P <0.05) .Conclusion: The combination of Tanreqing and Yanhu Ning can treat HFMD in children with definite curative effect. The two drugs have synergistic effect and inhibit the virus replication, which is superior to Ribavirin.